Marilena Loizidou is Professor of Cancer Nanotechnology and Deputy Director of the Division of Surgery and Interventional Science (SIS) at UCL. Marilena is also Head of the SIS Department at the Royal Free Campus. After her undergraduate training in Biochemistry (McMasters University, Canada), she moved to the University of Southampton where she obtained her PhD in Solid Tumour Biology and Pharmacology and became lead clinical scientist at the University of Southampton/NHS. She moved to UCL in 1993 to the academic department of Surgery, and became Head of Department in 2013.
Marilena has over 150 publications and has successfully supervised over 25 research fellows. She is co-Founder and Director of the MSc in Nanotechnology and Regenerative Medicine and the MSc in Surgical and Interventional Sciences.
Marilena’s research is in the area of targeted and stratified cancer therapy, by:
- Developing and evaluating imaging and targeted nano-therapeutic agents for solid tumours, mainly colorectal cancer, with a particular focus on the role of the fibrotic cancer stroma.
- Using tumouroids as testing platforms. Marilena co-invented tumouroids, which are 3D in vitro cultures of cancer that mimic the composition and architecture of solid tumours. Tumouroids are currently developed from cells from individual patients to test their response to different drugs and determine their potential for personalised medicine.