SESSION CHAIR - PROFESSOR GEOFF PILKINGTON
I have spent my entire career in brain tumour research, having started work on chemical neuro-carcinogenesis where I studied brain cancer stem cells and brain tumour development at the Middlesex Hospital Medical School in the early 1970s and subsequently spent 23 years at the Institute of Psychiatry, King’s College, London, latterly as Professor of Experimental Neuro-oncology. In 2003 I moved to the School of Pharmacy & Biomedical Sciences, University of Portsmouth, as Professor of Cellular & Molecular Neuro-oncology & Director of Research. I now head the Portsmouth Brain Tumour Research Centre, the largest laboratory-based Centre of its kind in the UK. Over the years the research focus of my group has been development of models for the study of intrinsic brain tumours, elucidation of the mechanisms underlying diffuse local invasive behaviour in glioma, delivery systems for passage of agents across the blood-brain barrier (BBB) and development of novel strategies for mitochondrial mediation of apoptosis in glioma. I have published numerous papers on the results of my research on human glioma and have developed various “all human” three-dimensional in vitro models to study brain tumour invasion and the BBB. At the University of Portsmouth I have established an excellent suite of laboratories and a host of state-of-the-art equipment in which to accommodate the Brain Tumour Research Centre.