ACTC CARDIFF promises to be a great event with a scientific programme lined up with something for everyone, whether you're a PhD student, Post Doc, Primary investigator or Professor, Research Scientist, Senior Scientist, Scientific Manager or Department Director.
Tuesday 4th June
9:30am: CONFERENCE OPENS
Advanced Cell Culture; 3D, Fluid Flow & Co-culture
9:30 - Ms Lauren Hyndman (University of Glasgow)
Mathematical modelling to guide experimental protocols for in vitro drug testing
9:50 - Ms Abigail Martin (University of Hertfordshire)
Immunocompetent human airway in vitro models for quantitative chemical assessments
10:10 - Dr Elisa Moschini (Luxembourg Institute of Science and Technology)
3D-tetraculture system at the air-liquid interface as a valuable tool for respiratory irritation and inflammation: case study using different silver-based nanomaterials
10:30 - Dr Victoria Kearns (University of Liverpool)
Development of Complementary in vitro and computational models of Drug Delivery Across the Outer Blood-Retinal Barrier
----------------------------------------- 11am: COFFEE BREAK -----------------------------------------
11:30 - KEYNOTE: Dr Uwe Marx (TissUse GmbH)
From organ-on-a-chip tools towards patients on chips – enforcing a paradigm shift in drug development
12:00 - Dr Anwar Palakkan (University of Edinburgh)
Embryonic stem cell derived anatomically realistic kidney organoids
12:20 - Professor Aline Miller (University of Manchester)
Engineering 3D Physiological Models and Cell Scaffolds using Self-Assembling Peptides; from lab to commercialisation
12:40 - Dr Elisa Budyn (Ecole Normale Superieure de Cachan)
3D bone self-assembly in a bone-on-chip
----------------------------- 13:00: LUNCH -----------------------------
14:00 - Dr Adithya Sridhar
Gut organoid monolayer model for infectious diseases research
14:20 - Dr Jan Markus
Drug Toxicity and Permeability Screening Using a 3D Reconstructed Human Small Intestine Tissue Model
14:40 - Dr Chiara Maria Mazzanti (Fondazione Pisana per la Scienza ONLUS)
Fluorescence intensity and lifetime imaging microscopy with the phasor approach to assess treatment response and disease progression of glioblastoma patient-derived organoids
15:00 - Professor Andrew Mearns Spragg (Jellagen)
----------------------------- 15:10: COFFEE BREAK -----------------------------
NOVEL MODELS FOR STUDYING NEUROLOGICAL DISEASES
15:40 - Keynote: Professor Roxana O Carare (University of Southampton)
Using quasi-vivo as a system for testing new therapeutic targets in Alzheimer’s disease
16:10 - Dr Prospero Civita (University of Portsmouth)
Towards a 3D all human in vitro model of glioblastoma multiforme for drug screening: glioblastoma and astrocyte interactions?
16:30 - Ms Jo Brown (University of Cardiff)
HiSpots®: A novel 3D model for the study of glioblastoma using ex vivo human tissue
16:50 - Ms Magda Gerigk (University of Cambridge)
Hijacking pre-existing blood vessels – a microfluidic approach to studying brain tumour progression
-----------------------------17:10: DAY 1 FINISH -----------------------------
19:00 – 19:15: GALA DINNER AT CARDIFF CASTLE
Wednesday 5th June
9:00am: DAY 2 BEGINS
In Vitro Models for Animal Replacement
9:00 - Dr Jan Turner (Safer Medicines Trust)
Human relevant in vitro models – barriers, initiatives and progress towards replacing animal methods in drug discovery
9:20 - Dr Pascale Guillot ( UCL)
Replacing the use of animals to study bone fragility
9:40 - Dr Marta Rutka (Promega, UK)
Factors to Consider for Developing In Vitro Cytotoxicity Assays to Replace Animal Testing
10:00 - KEYONTE: DR Helena Kandarova (SETOX)
Can we rely on the predictions derived from in vitro reconstructed human tissue models ?
----------------------------- 10:30am: COFFEE BREAK -----------------------------
DEVELOPMENTS WITHIN IN VITRO CANCER RESEARCH
11:00 - KEYNOTE: Professor Stephen Evans (University of Leeds)
Cells Under Stress: Microfluidic Determination of Single Cell Behavior and it's Potential for Aiding Diagnosis and Treatment.
11:30 - Ms Lekha Shah (University of Manchester)
Tumour progression in metastatic breast cancer cell lines: engineered in vitro models
11:50 - Dr Beate Rinner (Medizinische Universität Graz)
Metastatic melanoma during pregnancy - MUG-Mel3 cell line - an in vitro model
12:10 Dr Kathryn Bagot (BioIVT)
Development of a novel human in vitro 3d model for evaluating anti-cancer drugs
----------------------------- 12:30: LUNCH -----------------------------
13:30 - KEYNOTE: Professor Marilena Loizidou (University College London)
Tumouroids: complex 3d cancer mimetics for the assessment of drug efficacy
14:00 - Dr Dania Movia (Trinity College Dublin)
Multilayered Cultures of NSCLC cells grown at the Air-Liquid Interface allow the efficacy testing of inhaled anti-cancer drugs
14:20 - Dr Karen Pilkington (University of Portsmouth)
Interim findings from the SAToRI-BTR (A Systematic Approach To Review of In vitro models in Brain Tumour Research) project.
14:40 - KEYNOTE: Professor John Greenman (University of Hull)
Patient tissue on chip – a personalized medicine option?
----------------------------- 15:10pm: COFFEE BREAK -----------------------------
15:40 - KEYNOTE: Professor Trevor Dale (University of Cardiff)
The practical challenges of using organoids in drug discovery
16:10 - Dr Suzanne Randle (AstraZeneca, UK)
Recent developments in in vitro models to assess haemtox risk of novel cancer therapeutics
16:30 - Dr. ir. Eirini Velliou (University of Surrey)
Engineering a novel versatile 3D tool for accelerating cancer therapies from bench to bed: A case study on pancreatic cancer
-----------------------------17:00pm: CONFERENCE CLOSE -----------------------------